Diabetes, Heart, and Cardiovascular Diseases News Chronicle.      Article 298

A New Vaccine Which Targets Enteroviruses Could Prevent Type 1 Diabetes

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A study by researchers at the Karolinska Institutet (Sweden) and the University of Tampere (Finland) shows the prevention of type 1 diabetes (T1D) in a patient by targeting enteroviruses with a newly developed prototype vaccine.

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The prevention of type 1 diabetes in children (kids) with the enteroviruses vaccines developed by the researchers.

The researchers say that the viruses such as enteroviruses, mumps virus, rotavirus and rubella virus are causing the autoimmune condition, which can trigger type 1 diabetes (T1D) in humans (kids, children or teenagers).

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The Scandinavian researchers have developed a vaccine for the experiments. The researchers wanted to find out the role of the virus in the development of type 1 diabetes (T1D).

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The experiment on mice models shows that the new vaccine can protect and prevent type 1 diabetes (T1D) development in a person due to the virus without any severe adverse effects. They also found that the new vaccine can protect other signs of type 1 diabetes (T1D) such as damage to the pancreas.

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Now they are developing a vaccine at the University of Tampere to target more viruses which are causing the infections and subsequently triggering type 1 diabetes (T1D). The researchers are going to conduct a further study before starting a clinical trial on humans.

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The study was published on November 20, 2017, in the journal Diabetologia. Title of the article was "A Coxsackievirus B vaccine protects against virus-induced diabetes in an experimental mouse model of type 1 diabetes."
Doi: dx.doi.org/10.1007/s00125-017-4492-z

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Enterovirus: These are a group of viruses. They live in our gastrointestinal tract. Most of the enteroviruses do not cause a disease in our gastrointestinal tract.

The enteroviruses are more likely to cause the infections in infants and children because their immune system was not developed fully.

Adults infected with enteroviruses may likely to show mild symptoms or no symptoms. These viruses can cause common infections. The symptoms of enterovirus infections are.

  • A painful, harsh or dry throat
  • Sneezing
  • A cough
  • A runny nose
  • Body and muscle pains
  • A sore throat
  • Vomiting
  • Fever
  • Non-itchy skin
  • Pink eye or conjunctivitis (Madras eye)
  • Sores in the mouth
  • Breathing problems

Poliovirus is a group of enterovirus and causes poliomyelitis (polio or infantile paralysis). It is highly contagious and dangerous disease. These viruses will be transmitted via contact with an infected person.


Published on January 25, 2018


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