| Article 221 Published on August 5, 2017 |
Reversal Of Type 2 Diabetes, Weight Loss And Reduction In Muscle Fat With The Vegetarian Diet
A study on patients with type 2 diabetes shows a reduction in muscle fat and a double weight loss with a vegetarian diet compared with a low-calorie diet (a diabetic diet as per the recommendations of the European Association for the Study of Diabetes. EASD). A six-month study was conducted on 74 patients with type 2 diabetes with the consumption of either a vegetarian diet or with a low-calorie diet. The calorie intake in both groups was reduced by 500 calories to the level between 1,500 and 1,800 calories per day.
In the first three months or in the first half of the study, patients under the vegetarian diet have lost an average of 14 pounds and patients under the low-calorie diet have lost an average of seven pounds.
In the second half of the study, the participants have followed a similar diet but performed the aerobic exercises for an hour, three times a week. They gained muscle mass in that period and registered a little weight loss. The researchers have studied the adipose (fat-storage) tissue of the participants that store fat with the help of magnetic resonance imaging. The study has found the following.
- A similar loss of fat in the subcutaneous tissues in patients following both forms of diet.
- A subfascial fat loss and the intramuscular fat loss was observed in patients following a vegetarian diet.
- About 42 percent of the patients with a vegetarian diet have reduced the treatment to lower blood sugar level when compared with five percent of the patients under the low-calorie diet.
- A reversal of type 2 diabetes (T2D) was observed in three patients under the vegetarian diet.
An earlier study on patients of type 2 diabetes shows that the higher muscle fat is associated with the higher insulin resistance and an improvement in the functioning of insulin with the reduction in the muscle fat.
The authors say that the vegetarian diet not only causes a weight loss but also address the cause of type 2 diabetes. The following table shows the food items consumed by the participants of the study.
| The participants under the vegetarian diet || The participants under the Low-Calorie (Diabetic) Diet |
| Vegetables || Colorful vegetables |
| Grains || A quarter of lean protein |
| Legumes || A quarter of starch |
| Fruits || |
| Nuts || |
| One serving of low-fat yogurt || |
The lead author of the study was Dr. Hana Kahleova MD, Ph.D., director of Clinical Research, Physicians Committee, Washington DC, the United States. The study was published in the Journal of the American College of Nutrition. Title of the article was "The Effect of a Vegetarian vs Conventional Hypocaloric Diabetic Diet on Thigh Adipose Tissue Distribution in Subjects with Type 2 Diabetes: A Randomized Study".
A Single Dose Of The Glucagon-blocking Drug (REMD-477) Found To Be Effective In Reducing Insulin Need
A small study on 21 patients with type 1 diabetes (T1D) at the University of California, San Diego, United States shows improvement in the blood sugar (glucose) levels with a single dose of a human monoclonal antibody and an investigational glucagon-blocking drug called REMD-477. The study also shows a remarkable reduction in the insulin requirement in the patients. The study shows the following.
- More patients have achieved the target level for blood sugar (glucose) with REMD-477, compared with placebo.
- The insulin requirement was 26 percent less in patients using a drug REMD-477 when compared to insulin requirement in patients with other treatments.
Lead author of the study was Jeremy Pettus, MD, assistant professor of medicine, endocrinology department, the University of California, San Diego, the United States. The study was presented at the American Diabetes Association, 77th Scientific Sessions, San Diego Convention Center, the United States. Title of the presentation was "Glucagon-Blocking Drug Reduces Need for Insulin and Improves Blood Glucose Levels for Patients with Type 1 Diabetes".
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