About Long Rapid Short-Intermediate Insulin From Novo Nordisk
There are basically four types of insulin
Long-acting insulin and short-acting insulin are not compatible with each other and so not possible to combine them in a single injection. But Danish-based Novo Nordisk company developed co-formulation of both types of insulin in a single pen device. This co-formulation will simplify insulin treatment with fewer injections, flexible, affordable, convenient for people with diabetes.
About T-Cells And c-Rel Protein
White blood cells are of two types and both of them helps our body immune system. Bone marrow develops one type of white cell and it is known as "B-cells". The B-cells job is to produce antibodies. A lymphoid organ in vertebrates produces another type of white cells and known as T-cells (or T-lymphocytes). T-cells job is the body immune response. T-cells again can be classified as
c-Rel is a protein plays important role in B-cells production and survival.
Type 1 diabetes (T1D) is an autoimmune disease that affects 5% of the population and more than 30 million in U.S. citizens affected by diabetes. Type 1 diabetes (T1D) impairs T-cells or T-lymphocytes cells those are circulating in the body. When T-cells are impaired, subsets of T-cells are unchecked and destroy needed body cells such as insulin producing beta cells in the pancreas. With the destruction of insulin producing beta cells, an individual will be affected by type 1 diabetes (T1D).
A study by researchers from the Case Western Reserve University, Cleveland Ohio identified the root cause for an abnormal immune response for the type 1 diabetes (T1D). Researchers created genetically engineered mice model for the c-Rel protein experiment. Researchers say
Lead author of the study was Dr. Parameswaran Ramakrishnan Ph.D and the study findings were published in Diabetes.
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Published by Jammi Vasista, Chennai, India.