Diabetes, Heart, and Cardiovascular Diseases News Chronicle.      Article 236

An Enhanced Risk For Celiac Disease In Children With Type 1 Diabetes

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A study at the UNSW Medicine, Australia shows the prevalence of celiac disease (CD), an autoimmune disorder in kids or children with type 1 diabetes (T1D) due to the genetic association. The authors say that five percent enhanced risk of celiac disease (CD) among children with type 1 diabetes (T1D) compared to one percent risk among normal children.



An Enhanced for celiac disease in children with type 1 diabetes.

The researchers have checked the prevalence of celiac disease (CD) in 52,721 children and teens (aged less than 18 years) with type 1 diabetes (T1D). They used the registry of patients with type 1 diabetes from the United States, Australasia, the United Kingdom, and Germany/Austria. The prevalence of both type 1 diabetes (T1D) and celiac disease (CD) among children (or kids) vary with different countries. Their study shows the following.


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  • The overall prevalence of celiac disease (CD) was 3.5 percent, ranging from 1.9 percent in the United States to 7.7 percent in Australia.
  • The prevalence of celiac disease (CD) among girls was 4.3 percent compared to 2.7 percent among boys.
  • Children with celiac disease (CD) were diagnosed with type 1 diabetes (T1D) when they were at the age of 5.4 years compared to 7 years among children (or teens) without celiac disease (CD).
  • Children with celiac disease (CD) were likely to be short in height.

The authors say that it is important to regularly screen for the symptoms of celiac disease (CD) in kids. The lead author of the study was Dr. Maria Craig, UNSW Medicine, Kensington, New South Wales (NSW), Australia. The study was published on June 29, 2017, in Diabetes Care. Title of the article was "Prevalence of Celiac Disease in 52,721 Youth With Type 1 Diabetes: International Comparison Across Three Continents."
DOI: doi.org/10.2337/dc16-2508



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The Weight Gain Between Pregnancies Was Linked To The Development Of Gestational Diabetes

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A study at the University of Bergen, Norway, shows the higher risk of type 2 diabetes during the next pregnancy for those women who have gained weight after having a baby. An earlier study shows that the overweight before the conception or a high weight gain before the pregnancy is the risk factor for the development of gestational diabetes. Gestational diabetes during the pregnancy can cause an increase in the number of health complications to both mother and baby. The suggested pregnancy weight gain from the start of the pregnancy as per the National Academy of Medicine (NAM) (The previous name was the Institute of Medicine) is as follows.



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BMI of the
pregnant women
The suggested
pregnancy weight gain
Underweight
(BMI less than 18.5)
28 to 40 pounds
Normal weight
(BMI between 18.5 and 24.9)
25 to 35 pounds
Overweight
(BMI between 25 and 29.9)
15 to 25 pounds
Obese
(BMI over 30.0)
11 to 20 pounds

Weight gain between pregnancies linked to the development of gestational diabetes.

The researchers have investigated the risk of diabetes in 24,198 women who gave birth between 2006 and 2014. The study has recorded their body mass index (BMI) and the history of gestational diabetes. The study has observed the following.

  • The incidence of gestational diabetes was 1.8 percent among second pregnancies.
  • About 36 percent of the women have gained weight equal to or more than one BMI between the start of their first pregnancy and start of their second pregnancy. The risk of the development of diabetes during second pregnancy is more among these women compared to women whose weight was stable.
  • A double risk of gestational diabetes to the pregnant women who have gained two BMI compared with women who gained less than one BMI.
  • A five-fold enhanced risk of gestational diabetes to those of pregnant women who have gained more than or equal to four BMI.
  • They have observed the notable risk of gestational diabetes among those women whose weight was normal before their first pregnancy and gained weight during the subsequent pregnancies.
  • They also observed a lower risk of diabetes during the next pregnancy among overweight women who have lost body weight after the previous delivery.

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The lead author of the study was Linn Marie Sorbye, a public health researcher, Department of Global Public Health and Primary Care, the University of Bergen, Norway. The study was published on August 1, 2017, in the journal PLOS Medicine. Title of the article was "Gestational diabetes mellitus and interpregnancy weight change: A population-based cohort study."
DOI: doi.org/10.1371/journal.pmed.1002367



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Published on September 2, 2017

 


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