Diabetes, Heart, and Cardiovascular Diseases News Chronicle.      Article 200

An Increased Risk Of Heart Failure In Those Women Who Have Reached Menopause Early And Never Gave Birth

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A study at the University of California shows an increase in the risk of heart failure in those women who never gave birth to a child, and had an early onset of menopause. The researchers think that there is an association between heart failure and the sex hormone levels in a woman.


An association between early menopause and never giving birth and the risk of heart failure in women.

The level of sex hormones in a woman may change due to pregnancy, and menstruation.


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The researchers have analyzed the data of 28,516 post-menopausal women from the data of the Women's Health Initiative study. The researchers have done a follow-up study for 13.1 years.

The follow-up study shows that 5.2 percent of women are suffering from heart failure.


The study has found an association between early menopause and increased risk of heart failure in a woman. The risk can increase further if early menopause was due to the removal of the ovaries. The risk of diastolic heart failure (affecting the left side of the heart) can increase in those women who never gave birth.


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The lead researcher of the study was Dr. Nisha Parikh, the University of California, and the study was published in the Journal of the American College of Cardiology. Title of the article is "Reproductive Factors and Incidence of Heart Failure Hospitalization in the Women's Health Initiative."
DOI: dx.doi.org/10.1016%2Fj.jacc.2017.03.557



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The Benefits Of Cardiovascular And The Activation Of SIRT1 Enzyme With Resveratrol

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A study shows remarkable improvement in cardiovascular health effects of resveratrol (a natural compound) in patients with diabetes. Resveratrol is a polyphenol compound with antioxidant properties. This compound is found in food items such as red wine, berries (cranberries and blueberries), grapes, cocoa, and peanuts.



Reduction in aortic stiffness and the prevention of aging of arteries with the consumption of resveratrol.

The premature aging of the arteries can happen in patients with diabetes. Resveratrol may activate SIRT1. In an experiment, the researchers have found that resveratrol slows down the aging process of the arteries.


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The researchers wanted to study the health benefits of resveratrol. The current study was conducted on 57 overweight or obese patients with type 2 diabetes, aged 56 and above. The study shows the following health benefits.


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  • About 4.8 percent reduction in the aortic stiffness in patients with the regular consumption of 100 milligrams of resveratrol.
  • Among individuals with higher arterial stiffness at the study baseline, about nine percent decrease in the aortic stiffness with the consumption of 300 milligrams of resveratrol.

The researchers say that resveratrol can benefit patients with diabetes and has no health benefits to people without diabetes. The researchers say that a long-term follow-up study is required to find out the effects of the daily consumption of resveratrol supplements on the vascular function.


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The senior author of the study was Dr. Naomi M Hamburg, an Associate Professor of Medicine, Boston University School of Medicine, Massachusetts. The study was presented at the 2017 Scientific Sessions (ATVB/PVD 2017) on Arteriosclerosis, Thrombosis and Vascular Biology Peripheral Vascular Disease, Minnesota, the United States between May 4 and 6.



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Aorta: The aorta, the largest artery in the body, which begins at the left ventricle of the heart. The aorta carries blood from the heart to the body organs and the tissues through the aortic valve.

 

Published on May 31, 2017

 


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