Diabetes, Heart and Cardiovascular Diseases News Chronicle.  Diabetes, Cardiovascular and Heart Diseases
 Article 130
    Published on February 11, 2017

 

Risk With Enteroviruses In Children

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The Type 1 Diabetes Prediction and Prevention Study by the Finish researchers from the University of Tampere show higher events of enterovirus infection in children before the onset of the autoimmune process causing type 1 diabetes (T1D). Researchers analyzed a group of viruses called the enteroviruses in stools to find out the association with islet autoimmunity in patients with type 1 diabetes (T1D). Previous studies linked persistent enterovirus infections to multiple diseases. They also found the presence of these viruses in the pancreas and blood in individuals with type 1 diabetes (T1D).



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Enterovirus infections (HFMD, Encephalitis, Herpangina) in children was associated with type 1 diabetes (T1D).

Enterovirus infections may cause mild symptoms such as a headache, sore throat, fever and loss of appetite. Highly infected people may have the following symptoms.

  • Low levels of oxygen in the blood (hypoxia).
  • Common cold.
  • Paralysis.
  • Aseptic meningitis (inflammation in the brain and spinal membranes).
  • HFMD - Hand, foot and mouth disease.
  • Conjunctivitis (infective inner eyelids and outer membrane).
  • Encephalitis (brain inflammation due to infection).
  • Myopericarditis.
  • Herpangina (a type of viral illness in children).
  • Pleurodynia (severe pain in the rib muscles).

Twelve months before the first sign of damage to the beta cell, researchers found higher levels of enterovirus infection in children and the presence of islet autoantibodies. Researchers say further investigations are required to find out the mechanism and to understand the development of type 1 diabetes (T1D). There is a need to develop a vaccine against these viruses. The study was published in the journal Diabetologia.



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Stimulating Bone Stem Cells May Improve Bone Repair

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A patient with diabetes does not recover well from bone fractures. Bone healing is one of the many complications faced by patients with diabetes. A study by researchers from the Stanford University School of Medicine, Palo Alto, discovered a protein in diabetic mice can stimulate bone stem cells to heal the fracture in a better way. This discovery can lead to better treatment for bone repair in people with diabetes.



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Stimulating bone stem cells may improve bone repair, healing from a bone fracture in a patient with diabetes.

Researchers observed a reduction in the bone stem cell activity in mice during the development phase of diabetes. They also observed similar effects in bone samples of a patient with diabetes. Researchers observed improvement in the healing process when the protein was applied. Senior author of the study was Prof Michael T Longaker and the study findings were published in the journal Science Translational Medicine.



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Risk With Depression For Cardiovascular Diseases

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More than 350 million people were affected by depression. About 15 percent of cardiovascular deaths are due to depression. A study by the researchers from Helmholtz Zentrum Mnchen found that depression is a risk factor for cardiovascular diseases (CVD) in men and the amount of risk is as great as the amount of risk with obesity, high body mass index (BMI) and high cholesterol levels.



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Blood pressure, obesity, BMI, cholesterol, depression are the risk factors for cardiovascular diseases (CVD).

Researchers analyzed data from 3,428 men, aged between 45 and 74 years. Over a ten-year follow-up study was done on the participants. They analyzed the impact of depression over the following four major risk factors.

  • Smoking.
  • Obesity.
  • Hypertension.
  • High cholesterol levels.

They also found that a greater risk is associated with high blood pressure and smoking. Group leader of the study was Dr. Karl-Heinz Ladwig, Helmholtz Zentrum Mnchen (also a professor of psychosomatic medicine at German Centre for Cardiovascular Research (DZHK)) and the study was published in the Atherosclerosis.



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