Diabetes, Heart and Cardiovascular Diseases News Chronicle.  Diabetes, Cardiovascular and Heart Diseases
 Article 14
    Published on June 14, 2016


Risks With Artificial Sweeteners

Prof Jennifer Kuk from York University, Toronto says artificial sweeteners may help in cutting calories and weight loss. But sugar replacements such as artificial sweeteners changes to gut bacteria and can lead to glucose intolerance and increases the risk to type 2 diabetes (T2D). The study says artificial sweeteners may not be helpful to health and our body could not digest them. They may harm our health. Those consuming artificial Sweeteners recorded slightly higher BMI. The study was published in the Applied Physiology, Nutrition and Metabolism.



       
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Approval Of iGlarLixi

Investigational therapy drug for type 2 diabetes (T2D) from Sanofi, iGlarLixi is a combination of

FDA advisory committee approved this drug. The approval came from Endocrinologic and Metabolic Drugs Advisory Committee (EMDAC). US advisory panel says FDA should approve iGlarLixi.



       
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Risks To Gangrene

Gangrene will be developed in people affected with type 2 diabetes (T2D). Gangrene often requires amputation. Nearly 7,000 amputations happen in the UK. Diabetes damages every organ of the body. High glucose levels damage small arteries and restrict circulation of blood. Poor circulation of blood means our antibiotics cannot reach infection and amputation follow. Even if surgeon bypasses a blockage by inserting a stent to keep blood flowing, blockage happens again in another place.



       
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About NICE Report

NICE (the National Institute for Health and Care Excellence) says all children with diabetes should check following tests annually

  • Blood sugar levels
  • Growth
  • BP Blood pressure
  • Kidney function
  • Cholesterol
  • Eye screening
  • Foot examination

But almost 75% of the children in England and Wales were not undergoing annual health checks. But experts said that average blood glucose level (HbA1C) in children with diabetes fell for the 5th year. HbA1C is a marker that measures overall diabetes control. The most commonly missed checks are

  • Cholesterol levels testing
  • Foot examinations
  • Eye screenings



       
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Transplanting Melligen Cells

Prof Ann Simpson and her team developed "Melligen" cells. They are genetically engineered to produce, store and release insulin as per the requirement of our body for the treatment of type 1 diabetes (T1D). "Melligen" cells will be transplanted into humans by using "Cell-in-a-Box" technology as our immune system normally destroys foreign tissues. The team secured US patent for "Melligen" cells from US Patent and Trademark Office. Now the group is working with PharmaCyte Biotech to commercialize the "Melligen" cells.



       
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Trials With DiaRem Tool For Surgery

An accurate prediction system for the remission of diabetes after bariatric surgery was designed. The tool is inexpensive and easy to use. Researchers scored patients with DiaRem, tool based on age, insulin dependence, diabetes medication use and HbA1c levels. Annemarie Hirsch PhD, MPH Geisinger Institute in Pennsylvania published their findings in JAMA Surgery . The research was funded by the Geisinger Clinic.



       
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Risks With Kidney Transplantation

Wisit Cheungpasitporn, MD (Mayo Clinic in Rochester) conducted meta-analysis from the data of 12 separate studies and concluded that the patients seem to develop diabetes after kidney transplantation among those patients with autosomal dominant polycystic kidney disease (ADPKD). Researchers say that there is increased insulin resistance in ADPKD patients with normal kidney function. Other risk factors include

  • Hepatitis C virus
  • Obesity
  • Cytomegalovirus infection
  • Impaired fasting glucose
  • Ethnicity



       
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