Diabetes, Heart and Cardiovascular Diseases News Chronicle.  Diabetes, Cardiovascular and Heart Diseases
 Article 23
    Published on July 5, 2016


Risks With Air Pollution Linked CVD Risk

Researchers found that an individual exposed to high levels of air pollution for 3 months duration rises blood glucose levels and cardiovascular disease risks, especially in diabetes patients. The study was conducted between 2003 and 2012 with more than 73,000 adults in southern Israel. The study was led by senior author Dr. Victor Novack MD PhD, Soroka University Medical Center and Ben-Gurion University in Beer Sheva, Israel. The was published in the Journal of Clinical Endocrinology & Metabolism.



       
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Risks With Type 1 Diabetes (T1D) In Children

Meena Chhabra, a Delhi based diabetologist says cases of type 1 diabetes (T1D) among children have risen from 1% to 5% during the last couple of years in India due to obesity and poor diet. The main reason for the incidents of type 1 diabetes (T1D) in children is due to the destruction of beta cells which produce insulin. Symptoms in children for type 1 diabetes (T1D) are increased urination, hunger, thirst, infections and fatigue. Type 1 diabetes (T1D) usually starts in an individual at a young age while type 2 diabetes (T2D) starts in an individual during adulthood.



       
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About Hypo Hub Of Novo

Danish firm Novo Nordisk created online diabetes management resources (Hypo Hub) for UK patients to educate public on the signs and impact of hypoglycemia or hypos. The newly created platform encourages patients to talk about their hypoglycemia and take guidance. Hypoglycemia is a common complication with diabetes patients but patients may not recognize it. Hypoglycemia happens when blood glucose levels go too low. Symptoms of Hypoglycemia are

  • Blurred vision
  • Trembling
  • Hunger



       
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Usability Study Of WellDoc BlueStar Mobile App

A study conducted by WellDoc shows that large percentage of type 2 diabetes (T2D) patients were engaged with BlueStar mobile App and most of them sent mobile App reports to their care team. LifeScan's blood glucose monitor is going to be integrated with the BlueStar mobile App. BlueStar mobile App is free to download but need a prescription. BlueStar mobile App provides health management tools and real-time diabetes management guidance. BlueStar mobile App provides actionable information and reports with the blood glucose levels data provided by the patient.



       
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Device To Predict Diabetes

A research team developed a new diagnostic system to predict the onset of diabetes. Researchers developed a sensor which can trap specific molecules in the blood and give the signal for the onset of diabetes within 5 years. Positively diagnosed people will get the opportunity to change their diet and lifestyle. Prototype and trials were yet to take place but the team is hopeful of bringing the device into the market in 2/3 years time frame. Researchers belonging to Nottingham Trent University and Cardiff University.



       
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About Diabetes In Women

Higher health risks in diabetes women are heart disease, blindness, depression and urinary infection. Screening tests for diabetes are

  • Random plasma glucose test
  • Fasting plasma glucose test
  • Oral glucose tolerance test



       
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Risks With Mother's Gestational Diabetes To Daughters

The study conducted by Ai Kubo (Epidemiologist) shows early development of puberty in daughters can happen (2.5 times more likely) due to obesity and diabetes during pregnancy of the mothers. The study outcome is based on a sample of 421 girls and their mothers in Northern California. The author says understanding causes of early onset of puberty is key in designing prevention strategies. Adverse health risks increase with early puberty such as

The findings were published in the American Journal of Epidemiology.



       
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Diabetes Link To Depression

The risk of depression will double for a diabetes patient. Prof Dr. Sherita Golden at the Johns Hopkins University School of Medicine, says stress hormone cortisol will be produced due to depression and produced cortisol hormone leads to insulin buildup and finally to diabetes. Parts of the brain also can be impacted due to the high glucose levels.



       
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Transplanting Laboratory Grown Beta Cells

Dr. David K C Cooper during the 76th scientific session of ADA said approximately 1000 islet transplantations to patients with type 1 diabetes (T1D) have been performed during the last decade. But the problem with islet transplantations is the requirement is huge. Researchers conducted trials of genetically modified islets to non-humans and long-term results of the trials were successful. Researchers say it is possible to transplant islets of pigs to humans suffering from type 1 diabetes (T1D) and prevent diabetes-related complications. Dr. Chad A Cowan (Harvard Stem Cell Institute) and his colleagues are producing a new set of insulin producing beta cells from laboratory-grown stem cells. Difficulties with islet transplantations are

  • Laboratory-developed beta cells need a precise sequence of steps with different substances
  • Require stem cells of those who are compatible with type 1 diabetes (T1D) patient
  • To be transplanted laboratory islets needs a method of protection from the immune system

Producing islets in the laboratory and transplanting them into the human body by protecting them against the immune system is called regenerative medicine techniques. If this technique is successful, it is possible to treat other diseases such as cancer, sclerosis and Parkinson's disease.



       
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Risks With Antibiotics Usage

Findings of a study done by researchers from UBC Okanagan shows that prolonged and over usage of antibiotics accelerate the disruption of gut bacteria. The gut bacteria disruption leads to the onset of type 1 diabetes (T1D). They say early life events are critical and usage of antibiotics will alter normal development of gut and subsequent healthy body development. The study shows a link between bacteria, the immune system of the body and development of type 1 diabetes (T1D). Researchers say further study required to identify the bacteria that protects the body against type 1 diabetes (T1D) and the results may help us in development of specific antibiotics in future. The findings were published in the Nature Groups ISME Journal.



       
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Trials With Tradjenta Linagliptin Drug

Results from Helsinki T2D shows that type 2 diabetes (T2D) patients can use prescription based medicine Tradjenta (linagliptin) along with diet and exercise to lower blood sugar levels. This medicine is not intended for type 1 diabetic (T1D) patients or to patients suffering from diabetic ketoacidosis. 50% of the type 2 diabetes patients (T2D) have long-term problems with kidneys and kidneys treatment options are limited for them. High glucose levels in the blood can damage kidneys. The early stage of kidney disease (known as albuminuria) is when albumin protein of kidneys leaked into the urine. Tradjenta drug does not require dosage adjustment irrespective of renal function and it is once in a day therapy. Side effects of Tradjenta are the stuffy nose, sore throat, cough and diarrhoea (or diarrhea).



       
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