Diabetes, Heart and Cardiovascular Diseases News Chronicle.  Diabetes, Cardiovascular and Heart Diseases
 Article 37
    Published on August 5, 2016


Risks With Diabetes During Pregnancy

Gestational diabetes (GD) and pre-gestational diabetes may put fetus (growing inside the pregnant women) at risk during the pregnancy. If the women are already with type 1 (T1D) or type 2 diabetes (T2D) before pregnancy, then it is called pre-gestational diabetes. The high blood sugar levels developed during the pregnancy of a normal woman is called gestational diabetes (GD). The pregnant women should control her blood sugar levels. Otherwise, the fetus will be exposed to excess sugar levels and affects born baby even after birth. If the fetus is exposed to high sugar levels, then risks for born baby are.

  • The higher birth weight.
  • Injury to the baby during birth.
  • Premature birth or preterm (before 37 weeks of pregnancy).
  • The higher risk of respiratory distress syndrome (problems in the lungs).
  • Hypoglycemia

If the pregnant woman is an insulin-dependent, the born baby will be at a higher risk of obesity and birth defects in the heart, spinal cord and urinary tract.



       
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Risks With Early Or Late Menopause

A study by Dr. Erin LeBlanc, Kaiser Permanente Center for Health Research found that incidents of early or late menopause increase the risk of type 2 diabetes (T2D). Researchers analyzed 124,000 women. The ideal age for the end of menopause is between 45 and 55 years. Researchers have found 25% enhanced risk of diabetes if the woman reaches menopause before 46 years and 12% enhanced risk of diabetes if she reaches menopause after 55 years. Estrogen hormone protects the woman from diabetes. Once a woman reaches menopause, the estrogen hormone declines and her body fat and blood sugar levels increases. The study findings were published in the journal Menopause.



       
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Study With Metformin Drug In Preventing Preterm Birth

A team of scientists from the Cincinnati Children's found that metformin diabetes drug can play a significant role in blocking a cause of preterm or premature birth. The findings are based on the results from mice breed which are prone to premature birth. The study leads to the understanding of the molecular pathway of the premature birth and achieving a healthy and full-term birth. Researchers have found that the lack of p53 gene in the uterus leads to the premature birth. Researchers have found coordinating (and signaling) protein "sestrin 2" levels are low and it is associated with the p53 gene. Researchers treated mice models with the metformin diabetes drug. They found a reversal of early aging cycle of the molecular pathway and mice models gave full-term births. Research findings were published on July 25, 2016, in the Journal of Clinical Investigation.



       
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Benefits With Exercise For Obese Pregnant Women

A study done by the researchers from the Norwegian University of Science and Technology (NTNU) shows that exercise alone can prevent obesity, reduce blood pressure and prevent the development of gestational diabetes in women. Risks associated with obesity during pregnancy are.

Dr. Trine Moholdt is the principal investigator of the study and the findings were published in the PLOS Medicine.



       
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Risks With Reproductive Span In Women

A study analyzed 124,379 postmenopausal women aged between 50 to 79 years and found that less than 30 years of reproductive period durations are at 37 percent increased risk and more than 45 years of reproductive period durations are at 23 percent increased risk of type 2 diabetes (T2D). This may be because of low estrogen hormone production during the earlier and later ages of the pregnant women affecting negatively to body fat distribution and accumulation and contribute to type 2 diabetes (T2D). Study results were published in the journal of the North American Menopause Society.



       
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FDA Approval Of Adlyxin

The FDA approved French drugmaker Sanofi's drug, Lixisenatide as Adlyxin for the treatment of type 2 diabetes (T2D) for the adults in the US.



       
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