Diabetes, Heart and Cardiovascular Diseases News Chronicle.  Diabetes, Cardiovascular and Heart Diseases
 Article 174
    Published on April 29, 2017

 

Firefighters are at a risk of heart attack

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A study at the University of Edinburgh shows an increased risk of heart attack with a job involving high temperature such as a firefighting. In a study, 19 healthy and non-smoking people from the Scottish Fire and Rescue Service were subjected to an extremely high temperature. Researchers monitored the participants with the heart monitor. The researchers observed the following health issues in the participants after exposing them to an extremely high temperature.



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  • A high temperature in the core body even after three to four hours.
  • A thick blood formation. A thick blood (also known as hypercoagulability or hughes syndrome) causes 66 percent of the higher risk of potentially harmful blood clots.
  • There is no improvement with the medication or treatment.
  • A minor injury to the heart muscles.

Jobs involving high temperature (such as firefighting) can cause a thick blood (also known as Hughes Syndrome), a high-risk factor to a heart attack.

Researchers think that the loss of fluid in the body and the body response to inflammation has caused the thickening of the blood and a higher risk of blood clot. Researchers say the risk of heart attack with an extremely high temperature will be reduced if the people in a job involving a high temperature are well hydrated.


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This study was funded by the British Heart Foundation (BHF). Lead author of the study was Prof Nick Mills, a research fellow at the University of Edinburgh and the study was published in the Circulation.



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A new drug to lower LMPTP activity to restore the insulin sensitivity

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Researchers at the University Of California have developed a new drug in the form of a pill to reverse type 2 diabetes (T2D) by the inhibition of the low molecular weight protein tyrosine phosphatase (LMPTP) enzyme.

The new drug can restore the insulin sensitivity of the cells of the patient with diabetes. A study of the newly developed drug on the obese mice models with a high blood sugar (glucose) levels was successful in reversing the type 2 diabetes (T2D).



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The researchers say that LMPTP activity can lower insulin sensitivity of the cell. The weakened insulin response can increase the blood sugar levels in the body (a risk of type 2 diabetes). The newly developed drug can reduce the activity of an enzyme called LMPTP and restore the functionality of the cell and the insulin sensitivity.

The trial with mice models shows no adverse side effects. The researchers say more study on the new drug is required to prove the safety of the drug for the human trial.

Researchers are very optimistic that the new drug can be a new therapeutic strategy for the reversal of type 2 diabetes. The lead author of the study was Stephanie M Stanford and the study was published in the journal Nature.



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Cycling helps to lower the risk of cancer and cardiovascular diseases

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A study on 264,337 people over a period of five years at the University of Glasgow shows a lower risk of cardiovascular disease, premature death from any cause (mortality) and cancer if the person swaps the bus or car pass with a cycle. The daily walking can benefit the health of a person. But the benefits of walking are less than the benefits of cycling.



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Benefits of cycling
Lower risk
of cancer
Lower risk of
cardiovascular diseases
Lower risk of
premature death
45% 46% 41%

Benefits of walking
Lower risk
of cancer
Lower risk of
cardiovascular diseases
Lower risk of
premature death
No link 27% 36%

Cycling helps to lower the risk of cancer, premature death from any cause (mortality) and cardiovascular diseases (CVD).

The study was published in the British Medical Journal (BMJ).



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