The researchers from China have invented paper-based test strips to monitor the progression of the heart failure in patients. Heart failure patients require close monitoring of their condition to avoid emergency cardiac department visits. Heart failure disease can be monitored with brain natriuretic peptide (BNP) antigen and suppression of tumorigenicity 2 (ST2) antigen in the blood as they are linked to heart failure. Measuring above levels are useful in monitoring progression or advancement of the disease but the procedure require skilled staff and equipment.
The new test strips requires just 10mcL of blood from heart failure patient. The test strip will turn into a green dot with the presence of brain natriuretic peptide (BNP) antigen and into a blue dot with the presence suppression of tumorigenicity 2 (ST2) antigen. Blue or green color intensity increases with the concentration of BNP or ST2 antigen levels. Test strips blue or green colors indicate worsening of heart failure condition of the patient with the increasing intensity of the color. Both the patient and the physician can use these test strips to analyze and monitor heart failure disease in a patient. The blood sample can be analyzed and transmitted to the physician of the patient with the help of a mobile App. The physician can provide necessary treatment to heart failure patient based on the results.
Inventors tested the product with 38 heart failure patient's blood samples. Minimal levels of ST2 and BNP were detected successfully with the samples. Inventors compared their techniques or procedure with the Household Fluorescent Lateral Flow Strip Platform (UC-LFS platform) techniques approved by FDA. They found they are in a good linear correlation. Authors of the study were Feng Xu and Min Lin and the study findings were published in the ACS Nano.
An observational study done by the researchers at Penn State College of Medicine, Pennsylvania, United States shows a strong risk of heart disease with less than six hours of night sleep among those people with risk factors to diabetes (or poor glucose metabolism), heart disease and high blood pressure (BP) or hypertension. Less than 6 hours of night sleep doubles death risk with stroke or heart disease. Researchers monitored 1,344 individuals with mean age of 49 years for one night in the sleep laboratory and came to above conclusion.
Professor Jeremy Pearson, an associate director at the British Heart Foundation says those individuals struggling to get proper sleep or sleep for more than six hours during the night should speak to their GP to find ways to get proper sleep during night time. The study results show 39 percent of the study participants are with at least three risk factors (metabolic syndrome, a danger sign) such as
The study found modest death risk among those people who sleep more than 6 hours. Authors of the study say clinical trials should be done to find out whether the heart health and risk factors will improve with the increase in sleep duration along with lower levels of blood pressure and blood sugar. This study was funded by the National Heart, Lung, and Blood Institute and the American Heart Association (AHA). Lead author of the study was Dr. Julio Fernandez-Mendoza, an assistant professor, Penn State College of Medicine, Pennsylvania, United States and also a sleep psychologist at the Sleep Research & Treatment Center, the Penn State Health Milton S Hershey Medical Center. The study findings were published in the Journal of the American Heart Association.
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Published by Jammi Vasista, Chennai, India.