Diabetes, Heart, and Cardiovascular Diseases News Chronicle.      Article 250

The Predictive Factor For The Survival Of An Infant With Congenital Heart Disease (CHD)


A study shows that the chances for the long-term survival of the newborn with congenital heart disease (CHD) can be predicted with the birth weight. Congenital heart disease is also known as a congenital heart anomaly or a congenital heart defect. The study shows that the best chance for survival for five years will be for the post-term and with the most body weight. The study shows a poorer chance of survival of preterm (also early term or early birth) with a low birth weight (or lightweight, lighter). The authors say that a baby with the congenital heart disease (CHD) may require complex life-saving surgeries and a lifetime follow up.

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The post-term birth weight is a predictive factor for the survival of an infant with congenital heart disease (CHD).

The researchers have analyzed data of about 5,070 babies born between 1985 and 2003 from the Northern Congenital Abnormality Survey (NorCAS) registry, which records the congenital disorders (birth defects) in infants born to the residents of the North of England. The analytical study shows the following.

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Survival up to age Survival Chances %
Up to 5 years of age 87.1%
Up to 10 years of age 86.7%
Up to 20 years of age 85.2%

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The study also found the following.

  • The percentage of the born babies at term (born between 37 and 42 weeks of the pregnancy) with isolated congenital heart disease (CHD) and with average birth weight was 53.7 percent.
  • The highest 5-year survival rate of 97.7 percent in post-term babies with the highest birth weight.
  • The lowest 5-year survival rate of 78.8 percent in preterm babies with the lowest birth weight.

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The study also found that the survival rate can increase as the babies grow. A decrease in the risk of death (mortality) by seven percent with a year of increase in age. The researchers think that the reason for the decrease in the mortality was due to the new surgical innovations such as Fontan procedure, arterial switch operation, and advancements in neonatal (newborn children) care.

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Lead author of the study was Dr. Kate E. Best, Ph.D., the Institute of Health & Society, Newcastle University the United Kingdom. The study was published on July 21, 2017, in the Journal of the American Heart Association. Title of the article was "Survival, by Birth Weight and Gestational Age, in Individuals With Congenital Heart Disease: A Population-Based Study."
DOI: doi.org/10.1161/JAHA.116.005213

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Preterm: Also known as an early term or early birth baby. A baby born before 37 weeks of pregnancy.

Early birth: Please see preterm.

Post-term: Also known as prolonged pregnancy and refers to the baby born after 42 weeks of pregnancy.

Arterial switch: Also known as the Jatene procedure or arterial switch operation. This is an open heart surgical procedure.

Fontan procedure: Also known as the Fontan-Kreutzer procedure. This is a surgical procedure used on children with a single ventricle (univentricular) heart.

Congenital heart disease: Congenital heart disease is a structural problem of the heart at birth. Some of the risk factors are overweight (obesity) of the mother, poor nutritional food, alcohol consumption, tobacco use, born baby biological parents are being closely related, Rubella (also known as three-day measles or German measles) infection during pregnancy.

Congenital heart anomaly: Please see congenital heart disease.

Congenital heart defect: Please see congenital heart disease.


Published on September 20, 2017


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