Diabetes, Heart and Cardiovascular Diseases News Chronicle.  Diabetes, Cardiovascular and Heart Diseases
 Article 260
    Published on October 23, 2017

 

Weight Loss And Improved Blood Sugar Levels (glycemic Control) With An EndoBarrier Device

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An NHS trial for the treatment of type 2 diabetes (T2D) by the doctors at the City Hospital, Birmingham, England, shows an improvement in the blood sugar levels and a significant weight loss with a new device called the EndoBarrier device in obese (higher body mass index. BMI) people with an uncontrolled blood sugar (glucose) levels (type 2 diabetes. T2D).



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Weight loss and improved blood sugar (glucose) levels (glycemic control or HbA1c) with an EndoBarrier device.

The EndoBarrier device is a very thin and long plastic tube (or sleeve) (as illustrated in the image). This device will be passed down through the mouth into the small intestine and then unrolled. This device can prevent the absorption of excess calories from the food that we eat through its lining. This procedure is an endoscopic procedure and does not involve surgery. This device can be removed after 12 months.

Doctors have conducted the trial of the EndoBarrier device on 50 patients who are with an uncontrolled blood sugar (glucose) levels (type 2 diabetes. T2D) for over 17 years. Seventeen participants are under insulin treatment. The trial with the EndoBarrier device shows.


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  • An improvement in the insulin sensitivity, which may lead to a healthy blood sugar (glucose) levels (lower glycemia or HbA1c levels)
  • An improvement in the function of the islets in the pancreas resulting in improved insulin secretion. Insulin dosage was reduced from 100 units to 30 units per day in insulin-dependent patients of type 2 diabetes (T2D).
  • Reduction in the need for oral diabetes medications.
  • A decrease in blood pressure.
  • A decrease in the fat deposits in the liver.
  • Stimulation in the gut to release more hormones.
  • Weight loss of around 15 kg (33 lb).
  • Improvement in the fitness levels.

This study shows that the health benefits of the EndoBarrier device are similar to the health benefits of gastric bypass surgery. The latest study was presented at the annual meeting of the European Association for the Study of Diabetes (EASD), Lisbon, Portugal. Even though the results are promising, doctors say that a further study is required to find out the long-term effects on the weight loss and blood sugar (glucose) levels (HbA1c levels) with the EndoBarrier device.



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Reverse Type 2 Diabetes And Extend The Life Expectancy By Six Years By Eating A Low-calorie Diet

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Experts say that a sustained weight loss of around 15 kg or 33 lbs by eating a low-calorie diet can reverse (cure) type 2 diabetes (T2D). But most of the patients do not try to lose weight. Even if a patient achieves remission (no longer having diabetes) of type 2 diabetes (T2D) by losing body weight, patient and healthcare professional of the patient seldom acknowledge the achievement and record the remission of type 2 diabetes (T2D).



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Lose body weight by eating a low-calorie diet to reverse type 2 diabetes and extend the life expectancy by six years.

The current guidelines are advising patients of diabetes to lower the risks associated with cardiovascular diseases and high blood sugar (glucose) levels with drugs and lifestyle changes. The researchers say that the life expectancy will be reduced by up to six years and a higher risk of health complications in patients of diabetes compared with people without diabetes. An earlier study shows that the life expectancy of a patient with diabetes can be extended with weight loss.

Lead author of the study was Louise McCombie, RD Weight Management Specialist, School of Medicine, Dentistry & Nursing, the University of Glasgow, United Kingdom. The study was published on September 13, 2017, in the British Medical Journal (BMJ). Title of the article was "Beating type 2 diabetes into remission."
DOI: http://doi.org/10.1136/bmj.j4030



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