Diabetes, Heart, and Cardiovascular Diseases News Chronicle.      Article 265

Higher Risk Of Heart Attacks, Early Death And All-cause Mortality With High Levels Of HDL Or "GOOD" Cholesterol


The NHS guidelines say that the levels of HDL or "GOOD" cholesterol in an individual should be more than one mmol/liter, LDL cholesterol levels should be less than 3 mmol/liter and total cholesterol levels should be less than 5 mmol/liter. But the guidelines did not say the maximum levels of HDL cholesterol for an individual.

Higher risk of heart attacks, early death and all-cause mortality with high levels of HDL or GOOD cholesterol.

A current study shows the double risk of early death (or higher risk of all-cause mortality) with high levels of HDL or "GOOD" cholesterol. The study shows 106 percent enhanced risk of mortality in men and 68 percent enhanced risk of mortality in women with high HDL cholesterol levels compared with those individuals who are with normal or moderate levels of HDL cholesterol.

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The low HDL cholesterol levels in the bloodstream can also contribute to a higher risk of mortality. The study shows the individuals with moderate levels of HDL cholesterol are at the lowest risk of mortality.

The researchers came to the above conclusion after the completion of six years of follow-up study among 52,268 men and 64,240 women participants in Denmark. More than 10,500 deaths were registered in the participants during that period.

The researchers say the study completely changes the current understanding of the HDL or "GOOD" cholesterol and the effects on the heart health with high levels of HDL cholesterol.

The researchers say that the HDL cholesterol levels should be removed as an important health parameter and the focus should be on the levels of triglyceride and LDL or "BAD" cholesterol levels. The following table defines high and moderate levels of HDL cholesterol in the bloodstream as per the researchers.

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  High levels of HDL Cholesterol Moderate levels of HDL Cholesterol
Men > 3.0 millimoles/liter 1.9 millimoles/liter
Women > 3.5 millimoles/liter 2.4 millimoles/liter

The study results accounted for risk factors such as body mass index (BMI), age, alcohol consumption, tobacco use, physical activity and high blood sugar (glucose) levels (diabetes). But the study could not explain the cause and effect relationship between the risk of mortality and the levels of HDL cholesterol (either low or high).

The co-author of the study was Professor Borge G. Nordestgaard, Department of Clinical Biochemistry, Copenhagen University Hospital, Herlev, Denmark. The study was published on August 21, 2017, in the European Heart Journal. Title of the article was "Extreme high high-density lipoprotein cholesterol is paradoxically associated with high mortality in men and women: two prospective cohort studies."
DOI: doi.org/10.1093/eurheartj/ehx163

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Heart Specialist Dr. Ross Walker Says Too Much Of Exercise Can Lead To Cardiac Problems Such As Heart Attack


Preventative cardiology expert Dr. Ross Walker, Sydney, Australia, say too much of exercise (or workout) can increase the risk of cardiac diseases, especially in individuals aged more than 40 years. He says an individual should do exercise between three and five hours per week for good heart (or cardiac) health. But doing exercise over five hours per week can increase the risk of heart attack and heart diseases and no additional health benefits.

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The cardiologist and heart specialist say too much of exercise can increase the risk of heart attack.

Dr. Ross Walker had found a significant increase in the number of patients of a heart attack without risk factors to heart disease such as high blood pressure (or hypertension), obesity, (or high body mass index. BMI) or tobacco use. Overstretching of the body organs including heart is the possible reason for the increase in the heart attacks in people without risk factors to heart disease.

Dr. Ross Walker advice regular heart check-ups (or cardiac risk assessments) to those individuals who are aged over 40 years and want to continue the high level of physical and sporting activities. He also says that people playing competitive sports should focus on "moderate exercise" after reaching 30-35 years. They should undergo a regular cardiac risk assessment (or heart health checks) if they want to continue playing competitive sport.

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The functioning of the heart will be affected by the health factors such as high blood pressure (or hypertension), blood cholesterol levels, family history, body mass index (BMI), and tobacco use. The cardiac risk assessment will give the status of the risk factors for heart diseases.

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Published on November 8, 2017


The Diabetes News Chronicle does not provide medical advice, diagnosis or treatment. Information in Diabetes News Chronicle is to support and not to replace medical advice given by the surgeon or physician or doctor. The published article is not a medical advice by the OWNER of the "Diabetes News Chronicle" website or by the AUTHOR of the article.

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