Diabetes, Heart and Cardiovascular Diseases News Chronicle.  Diabetes, Cardiovascular and Heart Diseases
 Article 267
    Published on November 20, 2017

 

Kidney Failure, Amputations, Blindness, Heart Attack And Stroke By Delaying Insulin Therapy Among Patients Of Type 2 Diabetes

Ads

An uncontrolled high blood glucose levels over a period may lead to diabetes complications such as kidney failure, amputations, blindness, heart attack and stroke.


The risk of amputations, blindness, heart attack and stroke by delaying insulin therapy in patients of type 2 diabetes.

The study funded by Sanofi shows that 30 percent of the insulin-dependent patients of type 2 diabetes (to control high blood sugar levels) does not start insulin therapy when physicians advise them. On an average, patients with diabetes are delaying the start of the treatment by about two years and by the time the blood glucose levels may further increase.



Ads A simple diabetic nerve pain treatment program
See More Ads For "Cure To Diabetic Pain"

Researchers have examined the electronic medical records of 3,295 patients of diabetes between 2000 and 2014 at the Brigham and Women's Hospital, Boston, Massachusetts, United States. Their study shows that nearly one-third of the patients did not start the insulin injection therapy when physicians advise them. Patients are delaying the start of insulin treatment because.

  • Fear of injections or needles (needle phobia).
  • Patients by mistake to think that the use of insulin can cause diabetes complications. The patient should understand that prolonged high blood sugar levels (type 2 diabetes. T2D) are the real cause for the development of diabetes complications.

Senior author of the study was Dr. Alexander Turchin, MD, MS, Associate Professor, Harvard Medical School, Boston, United States. The study was published on September 14, 2017, in Diabetic Medicine. Title of the article was "Decline of insulin therapy and delays in insulin initiation in people with uncontrolled diabetes mellitus."
DOI: doi.org/10.1111/dme.13454



Ads Quickly burn off stubborn belly fat. Men and women. Any age.
See More Ads For "Lowering Body Fat"



        Twitter
If you like this article, please share it with a friend! Article address is (copy and paste the code below) :

Articles similar to this topic


Ads Human growth hormones (HGH) for physical stamina, lean muscle and weight loss
See More Ads For "Body Weight Loss"

1. Eating cocoa chocolate reduces blood sugar or glucose levels, obesity and increases insulin secretion
2. Raspberries could lower inflammation, high blood sugar or glucose levels and improves insulin sensitivity
3. High-intensity interval training (HIIT) workout reduces waist circumference, systolic blood pressure, insulin and blood sugar glucose levels
4. Insufficient sleep hours increases the risk of type 2 diabetes, insulin resistance and body fat in children
5. Lorcaserin reduces high blood sugar levels and increases insulin sensitivity in patients with type 2 diabetes
6. Urocortin 2 (Ucn2) gene transfer therapy improves insulin sensitivity and reduces blood sugar or glucose (HbA1c) levels
7. A single dose of glucagon receptor antibody found to be as effective in reducing insulin need

Ads Raspberry ketone max with a blend of green tea, chromium, caffeine and l theanine supplements to losing weight
See More Ads For "Body Weight Loss"

8. Prevention of heart diseases with an extra injection of insulin after meals in patients with type 1 diabetes
9. Amalgam Rx Launches iSage Rx Type 2 Diabetes App Which Automates Insulin Dosage
10. Regulation Of Insulin And Treatment Of Type 2 Diabetes With Stevia Extract

Ads A powerful treatment to take full control over your type 2 diabetes
See More Ads For "Reversal Of Diabetes"

 

 

 

Relief From Chronic Diabetic Nerve Pain Or Neuropathy By Blocking A Protein Called HCN2

Ads

About 25 percent of the patients of diabetes were affected by the disorders or damages from diabetic nerve pain, affecting the body including the arms, hands, feet and legs. The normal pain-relieving drugs may not provide relief to nerve pain because the pain in the sensory nerves is caused due to high blood sugar (glucose) levels (type 2 diabetes. T2D). Currently, there is no effective treatment for diabetic nerve pain.


Ads 21 Day rapid weight loss program
See More Ads For "Body Weight Loss"


A relief from Diabetic Nerve or Neuropathy, that affects the arms, hands, feet and legs by blocking a protein called HCN2.

A study by the researchers at the King's College London, United Kingdom, confirms the role of hyperpolarization-activated cyclic nucleotide- gated 2 (HCN2) gene or protein in the development of chronic diabetic nerve pain.


The researchers have conducted experiments on diabetic mice models. They found that overactive HCN2 gene can promote the pain or a burning sensation by inducing and maintaining electrical signals in nociceptive (a receptor) neurons. The researchers are successful in stopping the sensation of the nerve pain by "genetically deleting" or blocking HCN2 gene channels in the nociceptive (a receptor) neurons.

Currently, there are drugs with a selective mechanism to suppress the activity of HCN2 protein without affecting other organs (for example heart rate regulation). The researchers say that the painful diabetic neuropathy or chronic nerve pain may be treated by developing new drugs which can selectively target the HCN2 gene without disturbing other molecules.


Ads A "METABOLISM MINERAL" trick to losing weight
See More Ads For "Body Weight Loss"

The first author of the study was Dr. Christoforos Tsantoulas, Department of Pharmacology, King's College London. The senior author of the study was Professor Peter McNaughton, Wolfson Centre for Age-Related Diseases, King's College London, United Kingdom. The study was published on September 27, 2017, in the journal Science Translational Medicine. Title of the article was "Hyperpolarization-activated cyclic nucleotide-gated 2 (HCN2) ion channels drive pain in mouse models of diabetic neuropathy."
DOI: doi.org/10.1126/scitranslmed.aam6072



Ads A simple way to lose belly fat and unwanted body fat
See More Ads For "Lowering Body Fat"



        Twitter
Post a message on social media and mail to your friend. Article address is (copy and paste the code below) :

Articles similar to this topic


Ads Dietrine weight loss program helps you to losing weight and to reduce carbs, carbohydrates, and calories
See More Ads For "Body Weight Loss"

1. Risks With Shoulder Pain
2. Quell For The Treatment Of Rheumatic Condition With Muscular Pain
3. Association between frozen shoulder and type 2 diabetes
4. Treatment To Diabetic Neuropathy
5. Treatment With ReGenerCell For Diabetic Foot Ulcer
6. Diabetic foot ulcers (DFU) could be predicted with SmartMat ™ from Podimetrics
7. Risks With Diabetic Cardiomyopathy

Ads This can burn 348% more fat and calories
See More Ads For "Lowering Body Fat"

8. Obstructive sleep apnea or apnoea (OSA) increases retinopathy risk in type 2 diabetes
9. About Diabetic Shoes To Treat Neuropathy
10. Tropical Gel Heals Wounds And Ulcers Fast

Ads The proven 3-point method to melt away ugly body fat in just 15 minutes a day
See More Ads For "Lowering Body Fat"

 

 

 

Sitemaps

Sitemap 1   Sitemap 2   Sitemap 3   Sitemap 4


The Diabetes News Chronicle does not provide medical advice, diagnosis or treatment. Information in Diabetes News Chronicle is to support and not to replace medical advice given by the surgeon or physician or doctor. The published article is not a medical advice by the OWNER of the "Diabetes News Chronicle" website or by the AUTHOR of the article.


Published by Jammi Vasista, Chennai, India.
Email Jammi[no-space]Vasista1991[at]gmail[dot]com
Phone 91-944-578-3182.
Address Diabetes News Chronicle, No 40, Kaveri Street, Rajaji Nagar, Villivakkam, Chennai, India. Pin : 600049.