A multicenter study shows that a non-surgical stent placement into the narrowed and clogged artery due to the plaque buildup (called as atherosclerosis disease) could be a better treatment option compared to medicines alone.
In a three-year study, researchers followed 888 patients. Some of them are taking medications and others had undergone a non-surgical stent procedure (also known as coronary angioplasty or percutaneous coronary intervention. PCI). Researchers have found fewer urgent hospitalizations and less chest pain among those patients who had the early stent. Around 50 percent of the heart patients who are under medication alone have undergone surgery.
Even though a heart patient initially had to spend a lot of money for a stent, the patient can save money by lowering hospitalization costs. The initial costs will be evened out after three years. This study has found that there will be no increased costs after three years if a coronary artery disease (CAD) patient undergoes an early stent operation.
The lead author of the study was Dr. William Fearon, professor of Cardiovascular Medicine, the Stanford University Medical Center. The study was published on November 2, 2017, in the Circulation. Title of the article was "Clinical Outcomes and Cost-Effectiveness of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention in Patients With Stable Coronary Artery Disease: Three-Year Follow-Up of the FAME 2 Trial (Fractional Flow Reserve Versus Angiography for Multivessel Evaluation)."
An earlier study shows that the metabolic irregularities with a disturbance to circadian rhythms. A study by researchers at the National Autonomous University of Mexico, Mexico City, shows that the late night meals (meals after 8.00 pm) can increase the blood fat levels, the risk of type 2 diabetes (T2D), heart diseases and the waistline. The study also shows early meals will reduce the blood fat levels. The researchers say that an individual should avoid eating after 9.00 pm.
To know the changes to the overall health with an out-of-sync lifestyle, the researchers have conducted experiments on rat models by feeding snacks during their active phase and at the beginning of their rest period. The researchers have found higher fat levels (a risk factor for type 2 diabetes and heart diseases) in the blood with a meal at the beginning of the rest period. There was no change in the fat levels in the blood when researchers removed a part of the brain which regulates the 24-hour activity cycle (circadian rhythms).
They say that the late night eating is against the natural timing device (also known as a circadian clock or biological clock). The human body is synchronized with alternating periods of light and darkness. The nutrients in the bloodstream during night time will stick around our body for a longer period of time and ultimately absorbed by the fat tissues as our body was not ready for calories at the night time. But the study has found no spike in the blood fat levels with a change in the lunchtime.
According to researchers, the health of the people traveling through multiple time zones may not be affected if they perform daily routine activities according to home time zone.
The lead author of the study was Dr. Ruud M. Buijs, Ph.D., a neurobiologist. The study was published on November 7, 2017, in the Experimental Physiology. Title of the article was "The suprachiasmatic nucleus drives day-night variations in postprandial triglyceride uptake into skeletal muscle and brown adipose tissue."
Circadian rhythm: A 24-hour activity cycle of the body such as digestion.
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Published by Jammi Vasista, Chennai, India.