Diabetes, Cardiovascular and Heart Diseases  Article 272     Published on November 30, 2017

Life-saving CORolla heart-implant device for the treatment of diastolic heart (cardiac) failure

The survival chances of a heart failure patient are poor. Studies show more than 40 percent of the heart failure patients die within five years. About 50 percent of the deaths are due to diastolic heart failure.

Risks for diastolic heart failure increases with age. Diastolic heart failure events are common among those women who are with high blood sugar (glucose) levels (type 2 diabetes. T2D), hypertension (high blood pressure) and obesity (high body mass index BMI). There are no effective medications, drugs or treatments for diastolic heart failure.

CorAssist Cardiovascular Ltd, Haifa, Israel based start-up company gave a new hope for diastolic heart failure patients. The company has developed an innovative CORolla heart (cardiac) implant device. The CORolla is an elastic device to improve cardiac diastolic function. The procedure involved in the CORolla implant device is minimally invasive. This device will be implanted into the left ventricle of the heart while the heart is beating. The device improves the diastolic function of the heart by applying direct internal expansion forces on the septum and on the walls of the left ventricle.

This technology was developed by Dr. Yair Feld, a cardiologist at the Rambam Health Care, Haifa, Israel. Dr. Shay Dubi and Dr. Yotam Reisner were also associated with the CORolla implant device development. The first procedure was performed by a team of professionals led by Professor Gil Bolotin, director of the Department of Cardiac Surgery.

Robert MacLachlan, a Canadian aged 72 years (a diastolic heart failure patient) was the first patient to undergo an experimental, life-saving, CORolla heart-implant device in the Rambam hospital on August 28, 2017. Researchers received approval for up to ten clinical trials of CORolla implant from the Health Ministry.

       
If you like this article, please share it with a friend! Article address is (copy and paste the code below) :

Articles similar to this topic

1. About Revita DMR Device
2. Repairing damaged hearts after a heart attack and heart failure with self-healing heart cells by preventing Singheart RNA molecule
3. Abbott's HeartMate 3 LVAD gets FDA approval to treat heart failure
4. Androgen deprivation therapy (ADT), a prostate cancer treatment was associated with a higher risk of heart failure
5. Enlargement & thickening of the left ventricle and heart failure with weight gain
6. Stem Cell Plaster Could Help Heart Failure Patients
7. Test Strips Helps In Monitoring Health Of A Heart Failure Patient

Septum : A wall that divides into the left and right sides of the heart.

Diastolic heart failure : When blood did not fill the lower left ventricle of the heart during the diastolic (blood filling) phase, the amount of blood pumped out of the heart to body organs is less than normal. This condition is called diastolic heart failure.

A study shows type 2 diabetes (T2D) and coronary heart disease (CHD) could be treated with a single drug or pill

Type 2 diabetes (T2D) increases the risk of coronary heart disease (CHD), a major cause of premature death. Earlier studies could not find out the reasons behind the development of coronary heart disease (CHD) due to type 2 diabetes (T2D). A current study shows similar genes cause the development of both type 2 diabetes (T2D) and heart diseases and they can be prevented with a single drug or pill.

Scientists have found seven mutations (changes in the gene structure) after analyzing DNA in more than 250,000 individuals from the East Asian, South Asian or European descent. These similar gene mutations have increased the risk of type 2 diabetes (T2D) and heart diseases. Researchers have found that the incidents of 65 percent of heart failures and 48 percent of the heart attack in patients with type 2 diabetes (T2D) are due to these genes.

Scientists also found that the mutation of the ApoE gene lowers risk of coronary heart disease (CHD) but increases the risk of type 2 diabetes (T2D). Researchers say these phenomena have explained the reason for the reduction in "BAD" or LDL cholesterol levels in the bloodstream, but an increase in the risk of type 2 diabetes (T2D) with statin drug treatment.

Scientists say the risk of coronary heart disease and type 2 diabetes (T2D) could be lowered by treating both the conditions with a single drug (or pill) by identifying genetic variants associated with both the diseases. There are possibilities to develop type 2 diabetes (T2D) drugs with either neutral or beneficial effects on coronary heart disease (CHD).

Co-senior authors of the study are Dr. Danish Saleheen, MBBS, Ph.D., an assistant professor of Epidemiology, Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania and Dr. Benjamin F. Voight, Ph.D., an associate professor of Genetics, Perelman School of Medicine, University of Pennsylvania. The study was published on September 4, 2017, in the Nature Genetics. Title of the article was "Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease."

       
Post a message on social media and mail to your friend. Article address is (copy and paste the code below) :

Articles similar to this topic

1. Ghrelin Hormone Could Expand Diabetes Treatments And Hypoglycemia
2. Regulation Of Insulin And Treatment Of Type 2 Diabetes With Stevia Extract
3. Risk Of Pancreas Inflammation With Gliptin Treatment
4. SR10171 Drug For The Treatment Of Bone Disease And Diabetes
5. Treatment With New diabetes Drug Empagliflozin
6. Treatment With Revita
7. Treatment With Jentadueto XR

ApoE : ApoE gene helps in producing apolipoprotein E protein. This protein combines with lipid fats to form lipoprotein molecules. These molecules are responsible for the packaging of cholesterol and carry them in the bloodstream.

Site maps

Site map 1   Site map 2   Site map 3   Site map 4

The Diabetes News Chronicle does not provide medical advice, diagnosis or treatment. Information in Diabetes News Chronicle is to support and not to replace medical advice given by the surgeon or physician or doctor. Published article is not a medical advice by the OWNER of the "Diabetes News Chronicle" website or by the AUTHOR of the article.

Published by Jammi Vasista, Chennai, India.
Email Jammi[no-space]Vasista1991[at]gmail[dot]com
Phone 91-944-578-3182.
Address Diabetes News Chronicle, No 40, Kaveri Street, Rajaji Nagar, Villivakkam, Chennai, India. Pin : 600049.