Diabetes, Heart, and Cardiovascular Diseases News Chronicle.      Article 273

Increased Risk Of Gestational Diabetes And High Blood Sugar Levels (Hyperglycemia) With A Short Sleep Duration


There was a significant drop in the sleep duration during the last 20 years in the United States. About 16 percent of the men and 25 percent of the women are experiencing an insufficient sleep. A study shows an increased risk of gestational diabetes among pregnant women with a short sleep duration.

The risk of gestational diabetes and high blood sugar (glucose) levels (hyperglycemia) with a short sleep duration.

Researchers have conducted a meta-analysis on 17,308 pregnant women from eight earlier studies. The researchers have collected the self-reported sleep duration and the information related to gestational diabetes from the participants. They also measured the sleep duration with an accelerometer-based sleep tracker. The researchers also collected the data of participants (such as blood glucose levels and measured sleep duration) of 287 pregnant women with gestational diabetes from four additional studies. The researchers made these observations.

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* A likely 1.7 fold (or 70 percent) enhanced risk of gestational diabetes in the pregnant women if the average sleep duration is less than six hours.

* The study has found 2.84 fold (or 170 percent) enhanced risk of gestational diabetes in the pregnant women if the sleep duration was less than 6.25 hours per night compared with pregnant women whose sleep duration was more than 6.25 hours per night.

The researchers say that more research is needed to confirm whether the risk of gestational diabetes can be reduced by extending the sleep duration.

The lead author of the study was Dr. Sirimon Reutrakul, MD, an associate professor, Chicago College of Medicine, University of Illinois. The study was published on October 16, 2017, in the journal Sleep Medicine Reviews. Title of the article was "Short sleep duration and hyperglycemia in pregnancy: Aggregate and individual patient data meta-analysis."
DOI: doi.org/10.1016/j.smrv.2017.09.003

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Hyperthyroidism And Hypothyroidism Are Not Associated With Type 2 Diabetes


The researchers have conducted an 11-year follow-up study on the participants of the Tehran Thyroid Study (TTS), with and without type 2 diabetes (T2D), to gauge the risk factors for the thyroid disease and the number of patients affected with thyroid disorders. The number of participants in the study is 5,786 people (3,410 women and 2,376 men). Researchers analyzed records of both type 2 diabetes (T2D) and pre-diabetes patients aged more than 30 years.

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Thyroid dysfunction (hyperthyroidism and hypothyroidism) was not linked to high blood sugar (glucose) levels (type 2 diabetes. T2D).

They calculated the incidents of thyroid disorders and accounted for risk factors such as age, sex, triglycerides, body mass index (BMI), tobacco use, cholesterol levels, insulin resistance, blood pressure, thyroid stimulating hormone (TSH) and thyroid peroxidase antibody (TPOAb).

The study shows no higher incidence of thyroid disorders such as hyperthyroidism and hypothyroidism (both at the clinical and the subclinical stage) in patients with type 2 diabetes (T2D) compared with people without type 2 diabetes (T2D). Researchers say that there is no association between type 2 diabetes (T2D) and thyroid disorders. In this study, researchers excluded patients with the following health conditions.

  • Patients with thyroid disease.
  • Patients consuming the radioactive iodine.
  • Patients with a history of thyroidectomy.
  • Pregnant women.
  • Patients taking glucocorticoids, levothyroxine, methimazole, propylthiouracil or lithium.
  • Patients with a history of thyroid surgery.

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The author of the study was Dr. Azita Zadeh-Vakili. The study was published on October 3, 2017, in the PLoS One. Title of the article was "Thyroid dysfunction in patients with impaired glucose metabolism: 11 years follow-up from the Tehran Thyroid Study."
DOI: doi.org/10.1371/journal.pone.0184808

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Published on December 2, 2017


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