A study shows a link between retinal vein occlusion (RVO) and acute myocardial infarction (AMI) or heart attack
Earlier studies were inconsistent in establishing an association between acute myocardial infarction (AMI) or heart attack and retinal vein occlusion (RVO) disease. A current retrospective study done by researchers shows 21 percent enhanced risk of an acute myocardial infarction (AMI) or heart attack with retinal vein occlusion (RVO) disease.
Researchers think that when there are changes in blood vessels in the retina causing retinal vein occlusion (RVO) disease, there might also be changes in the blood vessels supplying blood to the heart causing acute myocardial infarction (AMI). With this belief, researchers say retinal vein occlusion (RVO) is associated with acute myocardial infarction AMI.
In this current study, researchers used the National Health Insurance Research Database (NHIRD) between 2001 and 2013 to identify 37,921 patients with retinal vein occlusion (RVO) disease with an average age of 62.4 years. Researchers compared them with 113,763 individuals without retinal vein occlusion (RVO). In their studies, researchers divided retinal vein occlusion (RVO) group into branch retinal vein occlusion (BRVO) and central retinal vein occlusion (CRVO). Researchers have done 5.5 years follow up studies.
During 13 year study, acute myocardial infarction (AMI) has occurred in 3.2 percent of patients in the retinal vein occlusion (RVO) group and 2.3 percent of the patients in the comparison group. After adjusting confounders, researchers found 21 percent increased risk of the development of acute myocardial infarction (AMI) in the retinal vein occlusion (RVO) group. Researchers adjusted their findings with other factors such as sex, age, obesity or body mass index (BMI), stroke, glaucoma, antithrombotic drugs usage and hyperviscosity syndrome. The adjusted hazard ratios for CRVO is 1.35 and that of BRVO is 1.15. Researchers say the risk with BRVO and CRVO to heart disease or acute myocardial infarction (AMI) are not same. They reported that CRVO patients are at higher risk of acute myocardial infarction (AMI) compared with BRVO group.
This study reminds specialists offering treatment to eye diseases and disorders (an ophthalmologist) about the risk of heart attack or acute myocardial infarction (AMI) while treating retinal vein occlusion (RVO) patients, particularly among patients with risk factors to heart diseases such as hypertension (or high blood pressure) and diabetes (high blood sugar or glucose levels). An ophthalmologist should refer heart disease risk patient to a heart specialist for an early diagnosis of heart disease to prevent future heart attack or acute myocardial infarction (AMI).
Lead researcher of the study was Yu-Yen Chen. The study findings were published on September 12, 2017, in the PLOS One. Title of the article was "Association between retinal vein occlusion and an increased risk of acute myocardial infarction: A nationwide population-based follow-up study."
Antithrombotic : Drugs to reduce the risk of the formation of blood clots in the bloodstream such as anticoagulants (blood thinners) and antiplatelet drugs (decrease platelet aggregation. Example aspirin).
Confounders : These factors may damage the final result of the study but researchers can not control or eliminate them in their experiments.
Hyperviscosity syndrome : Blood containing a higher percentage of cells increases blood viscosity. Due to high viscosity, blood may not move freely within the blood vessels causing the hyperviscosity syndrome.
Retinal vein occlusion : Blood from the retina will be taken away by tiny veins. Blockage in these veins obstructs blood flow causing retinal vein occlusion (RVO) disease. Blockage happens due to blood clots, hypertension (or high blood pressure BP), atherosclerosis and diabetes (high blood glucose levels).
The Diabetes News Chronicle does not provide medical advice, diagnosis or treatment. Information in Diabetes News Chronicle is to support and not to replace medical advice given by the surgeon or physician or doctor. Published article is not a medical advice by the OWNER of "Diabetes News Chronicle" website or by the AUTHOR of the article.
Published by Jammi Vasista, Chennai, India.