Diabetes, Heart, and Cardiovascular Diseases News Chronicle.      Article 281

A Quick Diagnosis Of Heart Damage And Heart Attack (Acute Myocardial Infarction. AMI) With The New Blood Biomarker


The ECG diagnosis (the current procedure) can easily diagnose the major heart attacks (Acute Myocardial Infarction. AMI). But the smaller or minor heart attacks are common and diagnosing them is challenging.

Diagnosis of the heart damage with the myosin-binding protein C (cMyC) at the NHS, United Kingdom.

The current test procedure involves checking for the biomarkers such as cardiac troponins to detect the heart damage (or a risk of heart attack ). This test will classify an individual as the low risk of heart attack if the cardiac troponins are untraceable and the patient will be discharged from the hospital immediately. But up to 85 percent of the patients of chest pain are being classified as the intermediate risk group, which requires an overnight stay at the hospital for further observation and blood tests, causing an increased medical cost.

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Now, the damage to the heart can be detected quickly within 20 minutes with a new procedure developed by the scientists at King's College London, United Kingdom (UK). The new test procedure will check the cardiac myosin-binding protein C (cMyC) in the blood.

The researchers have found that this biomarker in the blood is more sensitive after the damage to the heart muscle as its level increases rapidly compared to the cardiac troponins. A quick diagnosis of the damage to the heart muscle can be done with this new test.

The current test procedure is failing in the detection of the damage to the heart muscle. But the new test enables an accurate detection of the heart attack. The patients without heart attack symptoms can be sent home.

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A study funded by the British Heart Foundation (a charity organization) has conducted a trial with the new test procedure to detect the damage to the heart muscle on more than 2,000 patients of an acute chest pain in Europe.

The new test procedure has found no heart attack incidence in a double the number of patients compared to the current procedure. Researchers say that the new test procedure will be implemented on the NHS within five years.

The lead researcher of the study was Dr. Tom Kaier, BHF Clinical Research Fellow, King's College London. The study was published on September 26, 2017, in the Circulation. Title of the article was "Direct Comparison of Cardiac Myosin-Binding Protein C With Cardiac Troponins for the Early Diagnosis of Acute Myocardial Infarction."
DOI: doi.org/10.1161/CIRCULATIONAHA.117.028084

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Skipping The Breakfast Can Cause The Formation Of Atherosclerotic Plaques, Cardiovascular And Heart Diseases


A Spanish study corroborates the significance of taking breakfast for the health of the heart. This study shows a double risk of atherosclerotic plaques and cardiovascular diseases among those individuals who skipped the breakfast or if the total calories of the breakfast (in calorie) is less than five percent of the recommended daily calorie consumption compared to those individuals who ate high-calorie breakfast.

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Skipping breakfast can cause the formation of atherosclerotic plaques, cardiovascular and heart diseases.

Researchers in the current study has analyzed the health of 4,000 middle-aged people working in offices. Researchers monitored the events and the development of atherosclerotic plaques in them. Their routine consumption of breakfast was as follows.

  • 70 percent of the participants are under the category of low-calorie breakfast, consuming between five and 20 percent of daily calorie requirement.
  • 20 percent of the participants are under the category of high-energy breakfast, consuming more than 20 percent of daily calorie requirement.
  • Seven percent of the participants had fruit juice, coffee or tea or skipped breakfast.
  • Three percent of the participants are either had a very low-calorie breakfast or skipped breakfast.

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Researchers used ultrasound technology to find out the atherosclerotic plaques in all the participants. When compared with participants who are under the category of high-energy breakfast, the study shows:

  • Those participants who used to skip breakfast regularly had 1.5 times more atherosclerotic plaques.
  • Those participants who used to skip breakfast regularly or eating very little had 2.5 times more plaques in some part of the heart.
  • More chances of unhealthy lifestyle habits among individuals who skipped the breakfast regularly.

The lead author of the study was Irina Uzhova, a researcher from the Spanish National Center for Cardiovascular Research (CNIC), Department of Epidemiology, Atherothrombosis and Imaging (EAI), Madrid, Spain. The study was published on October 2, 2017, in the Journal of American College of Cardiology (JACC). Title of the article was "The Importance of Breakfast in Atherosclerosis Disease: Insights From the PESA Study."
DOI: doi.org/10.1016/j.jacc.2017.08.027

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Published on December 29, 2017


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