Diabetes, Heart and Cardiovascular Diseases News Chronicle.  Diabetes, Cardiovascular and Heart Diseases
 Article 297
    Published on January 24, 2018

 

A link between obesity and risk of type 2 diabetes

Ads

Obesity or a high body mass index (BMI) is the main risk factor for type 2 diabetes (T2D). More than 400 million people worldwide were affected by the obesity-induced type 2 diabetes.



Prevention of high blood sugar (glucose) levels, type 2 diabetes and insulin resistance associated with obesity.

Now, the researchers from the University of Texas Southwestern Medical Center identified the mechanism behind the development of type 2 diabetes associated with obesity (or overweight).

The pancreas secretes insulin, and insulin helps us in delivering glucose and oxygen from the bloodstream into cells to produce energy. Most of the glucose produced by the liver will be consumed by the muscles.


Ads Dietrine weight loss program helps you to lose weight and to reduce carbs, carbohydrates, and calories
See More Ads For "Body Weight Loss"

The researchers found that the insulin in the obese people was unable to pass through the cells that form the inner lining of blood vessels. As insulin could not deliver the glucose into cells, blood glucose levels increase, leading to the insulin resistance and type 2 diabetes. High blood sugar (glucose) levels is a risk factor for diseases associated with kidney, blood vessels (arteries) and vision (eye).

Immunoglobulins, a large Y-shaped antibody protein, helps the immune system to neutralize the external viruses and bacteria. Researchers say that the delivery of glucose by the insulin to muscle with the help of immunoglobulins is the main cause of the risk of type 2 diabetes associated with obesity.



Ads This can burn 348% more fat and calories
See More Ads For "Lowering Body Fat"

In experiments involving obese mice models, researchers found an enzyme needed for the transfer of insulin (with glucose and oxygen) from the blood to muscle was prevented due to an unpredictable chemical change in the immunoglobulins. A non-diabetic mouse will become a diabetic if it receives immunoglobulins from a mouse with type 2 diabetes. Researchers say an obese person is at similar risk.

In the study, researchers identified an agent that can prevent an unexpected chemical change in the immunoglobulins. Researchers are successful in testing the agent in preventing the high blood sugar (glucose) levels in mice models. Now, the researchers are planning to experiment in humans.


Ads Naturally reversing diabetes derived from the bible
See More Ads For "Reversal Of Diabetes"

Co-senior author of the study was Dr. Chieko Mineo, Ph.D., Associate Professor of Pediatrics, the University of Texas Southwestern Medical Center, Dallas, the United States. The study was published November 27, 2017, in the journal of clinical investigation. Title of the article was "Hyposialylated IgG activates endothelial IgG receptor FcγRIIB to promote obesity-induced insulin resistance." DOI : doi.org/10.1172/JCI89333



Ads The proven 3-point method to melt away ugly body fat in just 15 minutes a day
See More Ads For "Lowering Body Fat"



       
If you like this article, please share it with a friend! Article address is (copy and paste the code below) :

Articles similar to this topic


1. Link Between Accumulation Of Fat (in Muscle) And Insulin Resistance
2. Low Carbohydrate Diet Lowers Insulin Resistance
3. Type 2 diabetes protection with antioxidant foods containing Vitamin C & E, lycopene or flavonoids
4. Chronic Kidney Disease, Heart Disease & Diabetes Prevention Drugs From Forxiga Drug Maker AstraZeneca
5. Permanent dysfunction of blood vessels with pregnancy preeclampsia condition in women
6. Diet with high magnesium content can prevent type 2 diabetes
7. Increase In Diabetes And Insulin Resistance With Climate Change

Ads Green Coffee Bean Max contains antioxidants and chlorogenic acid to lose weight and to prevent obesity
See More Ads For "Body Weight Loss"
8. Increased risk of type 2 diabetes and insulin resistance with psoriasis severity or higher body surface area (BSA)
9. Obesity Worsen Type 2 Diabetes (T2D) Related Brain Abnormalities - Dementia, Cognitive
10. Prevention Of Diabetes
11. Prevention Of Type 2 Diabetes With Weight Loss Drug
12. The study shows a duration of the psoriasis disease increases the risk of inflammation in blood vessels, cardiovascular diseases, heart attack and stroke
13. Lower risk of obesity and type 2 diabetes with the consumption of whole grains and milled whole grains
14. Risks With Teenage BMI

Ads Use this simple trick to melt over 40 pounds of belly fat
See More Ads For "Lowering Body Fat"

 

 

 

Site maps

Site map 1   Site map 2   Site map 3   Site map 4


The Diabetes News Chronicle does not provide medical advice, diagnosis or treatment. Information in Diabetes News Chronicle is to support and not to replace medical advice given by the surgeon or physician or doctor. Published article is not a medical advice by the OWNER of the "Diabetes News Chronicle" website or by the AUTHOR of the article.


Published by Jammi Vasista, Chennai, India.
Email Jammi[no-space]Vasista1991[at]gmail[dot]com
Phone 91-944-578-3182.
Address Diabetes News Chronicle, No 40, Kaveri Street, Rajaji Nagar, Villivakkam, Chennai, India. Pin : 600049.