Diabetes, Cardiovascular and Heart Diseases  Article 298     Published on January 25, 2018

A study by researchers at the Karolinska Institutet (Sweden) and the University of Tampere (Finland) shows prevention of type 1 diabetes (T1D) development by targeting enteroviruses with a newly developed prototype vaccine. Researchers claim viruses such as enteroviruses, mumps virus, rotavirus and rubella virus are causing the autoimmune condition and subsequently to the development of type 1 diabetes (T1D) in humans (including kids, children and teenagers).

The Scandinavian researchers have created their own vaccine for their experiments to find out the role played by the virus in the development of type 1 diabetes (T1D). Their experiments with mice models show that new vaccine can protect and prevent type 1 diabetes (T1D) development due to the virus without any severe adverse effects. They also found the new vaccine can protect other signs of type 1 diabetes (T1D) such as damage to the pancreas. Now they are developing a vaccine at the University of Tampere to target more viruses causing infection and leading to type 1 diabetes condition (T1D). They are going to conduct further trials before starting human clinical trials.

The study findings were published November 20, 2017, in the journal Diabetologia. Title of the article was "A Coxsackievirus B vaccine protects against virus-induced diabetes in an experimental mouse model of type 1 diabetes." Doi : dx.doi.org/10.1007/s00125-017-4492-z

       
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Enterovirus : These are a group of viruses and live in our gastrointestinal tract. Most of the enteroviruses do not cause diseases in our gastrointestinal tract. Enteroviruses more likely to cause infections in infants and children because their immune system was not developed fully. Adult individuals infected with enteroviruses may likely show mild symptoms or no symptoms. These viruses cause common infections. Symptoms of infections caused due to enterovirus are.

• A painful, harsh or dry sensation in the throat
• Sneezing
• Cough
• Runny nose
• Body and muscle pains
• Sore throat
• Vomiting
• Fever
• Skin affected with non-itchy rashes
• Pink eye or conjunctivitis (or Madras eye)
• Sores in the mouth
• Breathing problems

Poliovirus is a group of enterovirus and causes poliomyelitis (polio or infantile paralysis). It is highly contagious and dangerous disease. These viruses will be transmitted by close contact from a infected person to another person.

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