A New Vaccine Which Targets Enteroviruses Could Prevent Type 1 Diabetes
A study by researchers at the Karolinska Institutet (Sweden) and the University of Tampere (Finland) shows the prevention of type 1 diabetes (T1D) in a patient by targeting enteroviruses with a newly developed prototype vaccine.
The researchers say that the viruses such as enteroviruses, mumps virus, rotavirus and rubella virus are causing the autoimmune condition, which can trigger type 1 diabetes (T1D) in humans (kids, children or teenagers).
The Scandinavian researchers have developed a vaccine for the experiments. The researchers wanted to find out the role of the virus in the development of type 1 diabetes (T1D).
The experiment on mice models shows that the new vaccine can protect and prevent type 1 diabetes (T1D) development in a person due to the virus without any severe adverse effects. They also found that the new vaccine can protect other signs of type 1 diabetes (T1D) such as damage to the pancreas.
Now they are developing a vaccine at the University of Tampere to target more viruses which are causing the infections and subsequently triggering type 1 diabetes (T1D). The researchers are going to conduct a further study before starting a clinical trial on humans.
The study was published on November 20, 2017, in the journal Diabetologia. Title of the article was "A Coxsackievirus B vaccine protects against virus-induced diabetes in an experimental mouse model of type 1 diabetes."
Enterovirus: These are a group of viruses. They live in our gastrointestinal tract. Most of the enteroviruses do not cause a disease in our gastrointestinal tract.
Poliovirus is a group of enterovirus and causes poliomyelitis (polio or infantile paralysis). It is highly contagious and dangerous disease. These viruses will be transmitted via contact with an infected person.
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Published by Jammi Vasista, Chennai, India.