Diabetes, Heart and Cardiovascular Diseases News Chronicle.  Diabetes, Cardiovascular and Heart Diseases
 Article 333
    Published on July 6, 2018


How does acute pancreatitis affect diabetes?

Advances in medical technology have helped in reducing the mortality over the years among patients with the acute pancreatitis disease. Patients who had recovered from acute pancreatitis are at risk of following events.


  • A decrease in the quality of life.
  • Recurrence of pancreatitis disease.
  • At the risk of exocrine pancreatic insufficiency (EPI).
  • Progression of pancreatitis disease to a chronic condition.

Researchers say acute pancreatitis causes about 250,000 hospital admissions every year and the number of hospital admissions is increasing every year.

An observational study finding shows higher incidents of type 2 diabetes among patients suffering from the acute pancreatitis disease. Earlier, experts thought that only people with chronic pancreatitis are at increased risk of type 2 diabetes. This study suggests that the acute pancreatitis disease increases the type 2 diabetes risk by six-fold within 3 months compared with people without acute pancreatitis disease condition.

Researchers have conducted a retrospective cohort study. Researchers used the Explorys database, which contains electronic medical records from 360 hospitals belonging to more than 50 million people. They searched those records for the patients diagnosed with the acute pancreatitis disease but without diseases such as type 2 diabetes, pancreatic cancer or chronic pancreatitis.


Researchers have found 104,000 first-time diagnosed patients with the acute pancreatitis disease. About 71 percent of them are in the age group of 18 and 65 years. About 77 percent of them were white, 16 percent of them were black and about 55 percent of them were women. About 5 percent of the patients are with the family history of type 2 diabetes.

The common health risk factors in the first-time acute pancreatitis disease diagnosed patients are.

They found following health risk factors contributing to a higher risk of the development of type 2 diabetes.

The study found the following factors are protecting the patients from the development of type 2 diabetes.

  • Older age. Age more than 65 years is contributing 26 percent lower risk.
  • Alcohol consumption is contributing 34 percent lower risk.
  • Smoking habit. But the study could not find out whether the protection is due to current or past smoking.
  • Being a White is contributing 54 percent lower risk.

Their preliminary study findings show the development of type 2 diabetes among 23 percent of the patients with the acute pancreatitis disease. About 75 percent of the newly diagnosed type 2 diabetes people are taking medications to control their high blood sugar levels. About 50 percent of those people were taking insulin therapy.


Six-fold higher incidents of type 2 diabetes among patients suffering from the acute pancreatitis disease.

The author of the study was Dr. Peter J Lee, MD, a Gastroenterology specialist, the University Hospitals Cleveland, Ohio, United States. The study findings were published as an abstract in May 2018 in the journal Gastroenterology. Title of the article was "Prevalence and Risk Factors for New Onset Diabetes Mellitus after Sentinel Episode of Acute Pancreatitis: A Population Based Study." DOI : doi.org/10.1016/S0016-5085(18)30698-X




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