Diabetes, Heart, and Cardiovascular Diseases News Chronicle.      Article 37

The Risk Of Diabetes During Pregnancy

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Gestational diabetes (GD) and pregestational diabetes may put the fetus (growing inside the pregnant woman) at a risk during the pregnancy.

If the woman is already with type 1 diabetes (T1D) or type 2 diabetes (T2D) before pregnancy, then it is called pregestational diabetes. The high blood sugar (glucose) level during the pregnancy of a normal pregnant woman is called gestational diabetes (GD).


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A pregnant woman should control her blood sugar levels. Otherwise, the fetus will be exposed to the excess sugar levels and affects the born baby. If the fetus is exposed to high sugar levels, then the born baby will be at risk of the following.

  • A higher birth weight.
  • An injury to the baby during birth.
  • Premature birth or preterm (before 37 weeks of pregnancy).
  • A higher risk of respiratory distress syndrome (problems in the lungs).
  • Hypoglycemia

If the pregnant woman is an insulin-dependent diabetes patient, the born baby will be at a higher risk of obesity and with birth defects in the heart, spinal cord and urinary tract.


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The Risk From An Early Or Late Menopause

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A study by Dr. Erin LeBlanc, the Kaiser Permanente Center for Health Research has found that the incidents of early or late menopause can increase the risk of type 2 diabetes (T2D).

The age for the end of menopause is between 45 and 55 years. The researchers have analyzed about 124,000 women.

The study has found 25 percent enhanced risk of diabetes if the woman reaches the menopause before 46 years and 12 percent enhanced risk of diabetes if the woman reaches the menopause after 55 years.


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The estrogen hormone will protect the woman from diabetes. Once a woman reaches the menopause, the estrogen hormone declines and her body fat and blood sugar levels can increase. The study was published in the journal Menopause.


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A Study On Metformin In Preventing Preterm Birth

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A team of scientists from the Cincinnati Children's has found that metformin can play a significant role in blocking a cause of preterm or premature birth.

This study shows the understanding of the molecular pathway of the premature birth and achieving a healthy and full-term birth. The researchers have done a study on mouse models, which are prone to premature birth.


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The study has found that the lack of p53 gene in the uterus may lead to premature birth. The researchers have found that a signaling protein "sestrin 2" levels are low and it is associated with the p53 gene.

The mouse models are administered with metformin. The researchers have found a reversal of early aging cycle of the molecular pathway and full-term births.

The study was published on July 25, 2016, in the Journal of Clinical Investigation.


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The Benefits Of Exercise In Obese Pregnant Women

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A study by the researchers from the Norwegian University of Science and Technology (NTNU) shows that exercise alone can prevent obesity, lower blood pressure and prevent the development of gestational diabetes in pregnant women.

The following are the risks associated with obesity during pregnancy in the women.


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Dr. Trine Moholdt is the principal investigator of the study. The study was published in PLOS Medicine.



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The Risk From Reproductive Span In Women

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A study on 124,379 postmenopausal women, aged between 50 and 79 years, has found 37 percent increased the risk of type 2 diabetes (T2D) with less than 30 years of the reproductive span and 23 percent increased risk of type 2 diabetes (T2D) with more than 45 years of the reproductive span.

This may be because of the low estrogen hormone during the earlier and later age of the women, which may negatively affect the body fat accumulation and distribution, leading to a higher risk of type 2 diabetes (T2D).


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The study was published in the journal of the North American Menopause Society.



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FDA Approval Of Adlyxin

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The Food and Drug Administration (FDA) approves Lixisenatide (brand name Adlyxin), a GLP-1 receptor, from Sanofi, France.

The drug is for the treatment of an adult patient with type 2 diabetes (T2D) in the United States.


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Published on August 5, 2016

 


The Diabetes News Chronicle does not provide medical advice, diagnosis or treatment. Information in Diabetes News Chronicle is to support and not to replace medical advice given by the surgeon or physician or doctor. The published article is not a medical advice by the OWNER of the "Diabetes News Chronicle" website or by the AUTHOR of the article.


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