Diabetes, Heart, and Cardiovascular Diseases News Chronicle.      Article 184

Elderly Women Are At Higher Risk Of The Development Of Diabetes While Taking Statins

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A study by researchers at the University of Queensland shows enhanced risk of the development of type 2 diabetes (T2D) among elderly women with statins medication. Even earlier studies proved the association between statins usage and the risk of the development of type 2 diabetes (T2D), insulin sensitivity and insulin secretion. But there are no studies among elderly women. But benefits with statins usage outweighed the risks to the development of diabetes.



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The Australian Longitudinal Study on Women's Health (ALSWH) started in the year 1996, had collected data of over 58,000 women in three age groups. They studied the health of the women under three age categories, 18-23, 45-50 and 70-75 years. Researchers focused more on the oldest group (or elderly women) during their ten years study period. After the study, the researchers concluded that 51 percent increase in the risk of the development of diabetes in elderly women, aged over 70 years with a prolonged usage of statin medication. They also concluded that additional increase in risk with higher doses of statin medication. The following table shows the risk of the new onset of diabetes in elderly women with the usage of statins drug.


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Statin dose Hazard ratio
Low dose 1.17
Middle dose 1.26
High dose 1.46
Very high dose 1.51

The ALSWH study finding suggests that elderly women taking statins are at higher risk of the development of type 2 diabetes (T2D). Healthcare professionals should monitor elderly women's blood sugar or glucose levels regularly and should take appropriate action after detecting an increase in the risk of type 2 diabetes (T2D). Lead author of the study is Mark Jones, MD, lecturer, the University of Queensland school of public health, Brisbane, Australia and the study findings were published in the March 2017 issue of the Drugs and Aging.



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Physical Exercise Increases Survival Chances After Stroke Or Heart Attack

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A study by researchers at the University of Copenhagen, Denmark shows an increase in survival chances after a heart attack in those people who are physically active. Researchers say physically active animals experience small intensity or less fatal myocardial infarctions or heart attacks. They wanted to know whether patient's physical activity and intensity of heart attacks (or myocardial infarctions) / recovery from them were linked together.



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Researchers compared exercise levels of 1,664 heart attack patients including 425 patients who lost their life immediately after a heart attack. They found that risk of death after a heart attack reduces with increase in physical activity levels. Following table describes risk reduction from death after a heart attack with physical exercise compared with those with no physical activity.


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Exercise intensity Death risk reduction%
Light intensity 32%
Moderate intensity 47%
High intensity 47%

The possible reasons for the recovery from the heart attacks (or myocardial infarctions) in those individuals who perform physical exercise are

  • The flow of blood may be improved with increasing levels of a chemical substance with respect to physical exercise. This chemical substance also reduces heart injury due to a heart attack.
  • Development of collateral blood vessels in the heart in those people who perform physical exercise. These collateral blood vessels will supply enough blood required by the heart after the blockage.

The researchers say the current study is an observational study and more studies are required to authenticate their findings. Co-author of the study was Professor Eva Prescott, at the University of Copenhagen and the study findings were published on April 12, 2017, in the European Journal of Preventive Cardiology.



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Published on May 11, 2017

 


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