Diabetes, Heart, and Cardiovascular Diseases News Chronicle.      Article 333

How Does Acute Pancreatitis Affect Type 2 Diabetes?

Know how to reverse type 2 diabetes.

Advances in medical technology have helped us in lowering the mortality (death) over the years in the patients with acute pancreatitis disease. Patients who had recovered from acute pancreatitis are at a risk of the following events.

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  • A decrease in quality of life.
  • A recurrence of the pancreatitis disease.
  • At the risk of exocrine pancreatic insufficiency (EPI).
  • The progression of the pancreatitis disease to a chronic condition.

A six-fold higher event of type 2 diabetes in the patients suffering from acute pancreatitis disease.

The researchers say that acute pancreatitis can cause about 250,000 hospital admissions every year and the number of hospital admissions is increasing every year.

An observational study shows the higher events of type 2 diabetes in the patients suffering from acute pancreatitis disease. Earlier, the experts believed that only people with a chronic pancreatitis are at an increased risk of type 2 diabetes. This study suggests that acute pancreatitis disease can increase the risk of type 2 diabetes by six-fold within three months when compared with people without an acute pancreatitis disease.

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The researchers have conducted a retrospective cohort study. The researchers used the Explorys database. This database contains electronic medical records of more than 50 million people from about 360 hospitals. They searched the records for the patients diagnosed with acute pancreatitis disease but without diseases such as type 2 diabetes, pancreatic cancer or chronic pancreatitis.

The researchers have found about 104,000 first time diagnosed patients with acute pancreatitis disease. About 71 percent of them are between 18 and 65 years. About 77 percent of them are White, 16 percent of them are black and about 55 percent of them are women. About five percent of patients are with the family history of type 2 diabetes.

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The common health risk factors in acute pancreatitis disease patients diagnosed for the first time are.

They found the following health risk factors are contributing to a higher risk of type 2 diabetes.

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The study also found the following factors are protecting the patients from type 2 diabetes.

  • Older age. Age more than 65 years is contributing to about 26 percent of the lower risk.
  • Alcohol consumption is contributing to about 34 percent lower risk.
  • Smoking habit. But the study could not find out whether the protection is from the current smoking or past smoking.
  • Being a White is contributing to about 54 percent of the lower risk.

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This preliminary study shows the risk of type 2 diabetes in 23 percent of patients with acute pancreatitis disease. About 75 percent of the newly diagnosed patients with type 2 diabetes are taking the treatment (medications, pills or drugs) to control the high blood sugar levels. About 50 percent of those people are taking insulin therapy.

The author of the study was Dr. Peter J Lee, MD, a Gastroenterology specialist, the University Hospitals Cleveland, Ohio, the United States. The study was published May 2018, in the journal Gastroenterology. Title of the article was "Prevalence and Risk Factors for New-Onset Diabetes Mellitus after Sentinel Episode of Acute Pancreatitis: A Population-Based Study."
DOI: doi.org/10.1016/S0016-5085(18)30698-X

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Published on July 6, 2018


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